{"product_id":"retatrutide-10mg","title":"Retatrutide 10mg","description":"\u003cp\u003eRetatrutide (also designated LY3437943) is a synthetic, investigational-grade peptide engineered as a unimolecular triple agonist targeting three key metabolic receptors simultaneously: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GcgR). This triple-receptor engagement profile distinguishes it from dual-agonist compounds and has made it a subject of extensive pre-clinical and clinical investigation.\u003c\/p\u003e\n\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003cul\u003e\n  \u003cli\u003e\n\u003cstrong\u003eProduct Name:\u003c\/strong\u003e Retatrutide\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCatalogue Number:\u003c\/strong\u003e RETA-010\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eUnit Size:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 2381089-83-2\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAlso Known As:\u003c\/strong\u003e LY3437943\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% (HPLC verified)\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAppearance:\u003c\/strong\u003e White to off-white lyophilised powder\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at −20°C; protect from light and moisture\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e 24 months from date of manufacture when stored correctly\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch Background\u003c\/h2\u003e\n\u003cp\u003eRetatrutide activates GLP-1R, GIPR, and the glucagon receptor in a balanced manner. The concurrent engagement of all three receptors is hypothesised to produce complementary metabolic effects in pre-clinical models: GLP-1R activation is associated with glucose regulation and appetite modulation, GIPR activation with potentiation of GLP-1–mediated responses, and GcgR activation with energy expenditure and hepatic lipid metabolism in laboratory settings.\u003c\/p\u003e\n\u003cp\u003eResearch into triple-agonist peptides such as Retatrutide has expanded significantly since 2020, with published Phase 2 data (Jastreboff et al., 2023, \u003cem\u003eNew England Journal of Medicine\u003c\/em\u003e) indicating substantial effects in human clinical trials on body weight and glycaemic parameters. All MMpeptides products are supplied strictly for in vitro and laboratory research use only.\u003c\/p\u003e\n\n\u003ch2\u003eReconstitution Guidelines\u003c\/h2\u003e\n\u003cp\u003eFor research use, reconstitute the lyophilised powder with sterile bacteriostatic water (available separately). Add solvent slowly to the vial wall — do not shake. Allow to stand for 2–3 minutes, then gently swirl until fully dissolved. Prepare working solutions at the concentration appropriate for your experimental model. Store reconstituted peptide at 4°C and use within 28 days; do not freeze reconstituted solution.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Use Only\u003c\/h2\u003e\n\u003cp\u003eThis product is intended exclusively for laboratory and in vitro research purposes. It is not approved for human or veterinary use and is not a medicinal product. MMpeptides supplies research-grade compounds to qualified researchers only. All applicable regulations regarding the purchase and use of research peptides in your jurisdiction must be observed.\u003c\/p\u003e","brand":"MMpeptides","offers":[{"title":"Default Title","offer_id":57753495798091,"sku":"MMP-RETA-10","price":54.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/8394\/0171\/files\/retatrutide-10mg-peptide-vial-mmpeptides_png_137779a5-543b-4d74-a923-1b4fd7a0a2d3.png?v=1783025412","url":"https:\/\/mmpeptides.co.uk\/products\/retatrutide-10mg","provider":"MMpeptides","version":"1.0","type":"link"}